Juan Pablo Lewinger

Dr. Juan Pablo Lewinger is Associate Professor of Clinical Population and Public Health Sciences at the University of Southern California. His research program focuses on genetic epidemiology, statistical genetics, and gene-environment interactions in cancer development and prevention.

His primary research investigates:

• Gene-environment interactions in colorectal cancer
• Polygenic risk score development
• Statistical methods for omics data
• Liquid biopsy biomarkers for cancer detection
• Nutritional and pharmacological cancer prevention

Recent methodological contributions include hierarchical Cox models for genomic data, two-step testing for gene-environment interactions, and pathway polygenic risk scores. His applied research examines how genetic factors modify associations between lifestyle factors (diet, smoking, medications) and cancer risk.

Dr. Lewinger develops novel statistical approaches for analyzing high-dimensional genomic data in epidemiological studies, with applications in colorectal, ovarian, and other cancers.