Jozien Goense

Jozien Goense is an Associate Professor at the University of Illinois at Urbana-Champaign (UIUC), holding joint appointments in the Department of Psychology and Department of Bioengineering. She is also affiliated with the Beckman Institute for Advanced Science and Technology and the Neuroscience Program. Her primary research focuses on biomedical imaging, particularly functional MRI (fMRI) and its applications in understanding neurovascular coupling and cortical layer-specific activity. She is recognized for contributions to high-resolution fMRI methodology and laminar imaging techniques.

Her work integrates advanced MRI techniques with neurophysiological studies, often using non-human primate models to validate findings in human studies. She has pioneered layer-specific fMRI approaches to map activity across cortical layers, particularly in the motor and visual cortices. Her expertise includes ultra-high field MRI (7T+), BOLD signal modeling, and software development for neuroimaging analysis (e.g., LayNII).

Key research themes include the physiological basis of BOLD responses, neurovascular coupling mechanisms, and the application of laminar fMRI to study brain function in health and disease. She has collaborated extensively with neuroscientists, engineers, and clinicians to advance imaging technologies and their translational potential.

Publications highlight her contributions to understanding dopamine and acetylcholine effects on neurovascular responses, resting-state gamma-band abnormalities in schizophrenia, and the development of high-resolution imaging protocols. Her work bridges basic science and clinical applications, including studies on vascular contributions to dementia and neuropharmacology.

She has received the Beckman Seed Grant as part of a Bioengineering Faculty team, supporting innovative research initiatives. Her lab employs cutting-edge imaging tools and multidisciplinary approaches to unravel brain function at cellular and systems levels.