Jouke Jan Hottenga

Jouke Jan Hottenga is a Visiting Research Fellow at the Vrije Universiteit Amsterdam, affiliated with the Faculty of Behavioural and Movement Sciences (Biological Psychology department) and the Amsterdam Public Health (APH) research institute's Health Behaviors & Chronic Diseases and Personalized Medicine divisions. His work focuses on genetic and epigenetic mechanisms underlying complex traits, including psychiatric disorders, neurodevelopmental outcomes, and environmental interactions. He has contributed to large-scale genome-wide association studies (GWAS), twin studies, and polygenic risk score analyses.

Key research interests include the genetic basis of developmental milestones, mental health, and chronic diseases. Hottenga has co-authored over 498 publications, with recent work emphasizing the role of genetic variants in income-related health disparities and the epigenetic influences of asthma polygenic burden. He teaches courses on genome-wide association methodologies and collaborates internationally on projects like the Netherlands Twin Register.

Notable contributions include studies on twin zygosity assessment, ADHD polygenic risk scores, and the genetic architecture of female fertility. His datasets and software contributions highlight expertise in molecular genetics, metabolomics, and epigenetic analyses.