
معرفی
Dr. Jorge Bernardino de la Serna is an Associate Professor in Inhalation Toxicology and Pharmacology at Imperial College London’s National Heart and Lung Institute, Faculty of Medicine. He leads the Mechanisms in Inhalation Toxicology, Physiopathology and Pharmacology (MITP2) group, focusing on multidisciplinary research spanning synthetic biology, biophysics, and nanomedicine. His work integrates organ-on-a-chip models with advanced microscopy to study molecular interactions in the alveolar-capillary barrier during inhalation exposures. He holds fellowships from the Royal Microscopical Society, Royal Society of Biology, and Royal Society of Chemistry.
Education: BSc/MSc in Chemistry and Biochemistry from the University Complutense of Madrid, followed by a PhD in Biochemistry. Postdoctoral training included roles at the University of Southern Denmark (MEMPHYS), University of Oxford, and the Max Planck Institute for Biophysical Chemistry under Nobel Laureate Prof. Stefan Hell. Non-academic experience includes a Staff Scientist position at the Rutherford Appleton Laboratory’s Central Laser Facility.
Research emphasizes understanding how inhaled substances affect lung cell behavior through lipid-protein interactions, super-resolution microscopy, and nanocarrier design. Key areas include aerosol toxicology, surfactant function, and drug delivery systems.
Awards include recognition for contributions to microscopy and biomaterials. Active in mentoring PhD and postdoctoral researchers, and collaborates across multiple Imperial College research networks (e.g., Membrane Receptor Network, Organ-on-chip). His lab develops novel imaging techniques and in vitro models to bridge nanoscale mechanisms with clinical applications.
