Jon Clayden

Jon Clayden is an Associate Professor at University College London (UCL), affiliated with the UCL Great Ormond Street Institute of Child Health and the Developmental Neurosciences Department. His research focuses on understanding brain connectivity and information processing, particularly in pediatric populations, using advanced neuroimaging techniques like diffusion MRI. He develops computational methods for image analysis and applies them to clinical problems in child health.

Education: PhD in Developmental Neurosciences from the University of Edinburgh (2007), MSc in Neurosciences from the University of Edinburgh (2004), and MA in Natural Sciences from the University of Cambridge (2002).

Research Interests:

• White matter microstructural development
• Pediatric neuroimaging
• Neurological disorders in children
• Functional and structural connectivity
• Machine learning in medical imaging

His work explores how brain networks change in disease and development, with applications to conditions like sickle cell anemia, epilepsy, and prematurity. He has contributed to tools like TractoR and the Neuroconductor R platform for reproducible neuroimaging analysis.

Collaborations: Involved in projects such as the TRIDENT Preclinical Trials (funded by a $24M NIH grant) and the Neurodesk open-source initiative. Active in open science and methodological improvements for MRI techniques.