John R. Jimah

John R. Jimah is an Assistant Professor of Molecular Biology at Princeton University, where he leads the Jimah Lab in Guyot Hall, M160. His research focuses on the structural and molecular mechanisms of membrane remodeling in human cells and malaria parasites using cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET).

His educational background includes a B.A. in Molecular Biology from Colgate University and a Ph.D. in Biology and Biomedical Sciences from Washington University in St. Louis. He completed postdoctoral training at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, as a Nancy Nossal Fellow and NIGMS MOSAIC Scholar.

Dr. Jimah's research spans two major domains: membrane remodeling in human cells, particularly in endocytosis and organelle biogenesis, and structural cell biology of malaria parasites. His work aims to uncover the molecular basis of cellular processes that can inform new therapeutic strategies against malaria and related diseases. He employs multidisciplinary approaches integrating structural biology, biochemistry, biophysics, and cell biology.

The recent publications highlight a strong trend in structural mechanisms of membrane dynamics, including dynamin function, clathrin lattice architecture, and pathogen traversal proteins like CelTOS. His work bridges fundamental cell biology with translational applications in infectious disease.

• Chancellor’s Graduate Fellowship Program
• Nancy Nossal Fellow
• NIGMS MOSAIC Scholar

Dr. Jimah advises emerging scientists through his lab at Princeton. While specific grant details are not listed, his fellowships and research focus suggest strong support from NIH and other major funding bodies. His lab investigates membrane fission, parasite-host interactions, and structural mechanisms of disease, contributing to both basic science and drug development.

The Jimah Lab at Princeton University is actively engaged in cutting-edge structural biology research, combining cryo-EM/ET with biochemical and cellular assays to understand how membranes are remodeled in health and disease. The lab studies both human cellular machinery and pathogenic systems, particularly malaria parasites, to uncover conserved and unique mechanisms.