John Liu

John Liu is a Physician Scientist at the University of California, San Francisco (UCSF), conducting interdisciplinary research in cancer biology and functional genomics. He holds a PhD in Biomedical Sciences from UCSF and an MD in Medicine from the same institution, with a current Radiation Oncology Residency at UCSF. His work focuses on advancing treatments for malignant brain tumors through CRISPR-based genetic screening and epigenetic engineering, targeting mechanisms of radiation resistance and epigenetic regulation in cancers.

• PhD, Biomedical Sciences, University of California, San Francisco (2017)
• MD, Medicine, University of California, San Francisco (2019)
• Radiation Oncology Residency, University of California, San Francisco (2024)

Liu's research spans three primary areas: (1) discovering novel cancer targets via functional genomics, particularly CRISPR screens; (2) investigating DNA damage response pathways in radiation therapy resistance; and (3) pioneering epigenetic editing strategies for precision oncology. His recent articles highlight applications of CRISPR technology in understanding tumor heterogeneity, meningioma evolution, and lncRNA roles in cancer progression.

Scientific recognition includes the CRISPR Cures for Cancer Initiative Pilot Award (2023-2024), Sontag Foundation Young Investigator Award (2022-2023), and RSNA Roentgen Research Award (2020-2024). Liu's work has been supported by NIH funding (F30NS092319) for studying neurogenesis-regulating long noncoding RNAs.