John Altin

John Altin is an Associate Professor at TGen's Immunology and Microbial Genomics Division, conducting cross-disciplinary research at the intersection of adaptive immunity, genomics, and biotechnology. His work focuses on high-dimensional immune profiling using advanced platforms like PepSeq and MHC-PepSeq for studying immune responses across $10M+ research programs. Key contributions include understanding T cell regulation pathways and developing serological tools for infection tracking.

• Immunology and Microbial Genomics Division, TGen
• Co-developer of PepSeq platform
• Recipient of >$10M research funding

His research spans infectious disease immunology (SARS-CoV-2, tuberculosis, malaria), autoimmune mechanisms (type 1 diabetes), and biotechnological innovations in antibody/TCR analysis. Publications demonstrate cross-reactive immunity patterns and high-dimensional immune profiling across human and animal populations.

Laboratory members include Sophia Carvalho (PhD), Heather Mead (PhD), Jorge Soria-Bustos (PhD), and Erin Kelley (MS). Collaborations extend to Prognosys Biosciences, SpaceX research, and Arizona clinical institutions. Current work emphasizes longitudinal infection tracking and vaccine response dynamics in immunocompromised populations.