معرفی
Dr. Johan Vande Voorde is a Senior Research Fellow at the School of Cancer Sciences, University of Glasgow, and Associate Group Leader at the CRUK Scotland Institute. His research focuses on metabolic crosstalk between the host and tumors, with particular emphasis on gut microbiome interactions in cancer and metabolic determinants of cancer-associated cachexia.
His educational background includes:
- PhD, Rega Institute, KU Leuven, Belgium (2013)
- MSc, Biological Sciences, University of Amsterdam, the Netherlands (2007)
- Professional Bachelor (Biochemistry), KH Leuven, Belgium (2005)
Dr. Vande Voorde's research investigates how cancer cells undergo metabolic rewiring to sustain proliferation and survive in hostile environments. His laboratory specifically examines metabolic interactions between the gut microbiome and host cells in colorectal cancer, and studies the mechanisms underlying cancer-associated cachexia - a wasting syndrome with no current cure. His work utilizes advanced preclinical cancer models and patient samples to identify metabolic vulnerabilities for therapeutic targeting.
Analysis of his publication record reveals a strong trajectory in cancer metabolism research, with increasing focus on metabolic profiling, tumor microenvironment interactions, and physiological relevance of cancer models. His recent work demonstrates expertise in spatial metabolomics, amino acid transport mechanisms, and metabolic vulnerabilities across multiple cancer types including colorectal, prostate, and breast cancers.
His notable achievements include:
- Cancer Research UK Career Development Fellowship (2024)
- Lord Kelvin/Adam Smith Leadership Fellowship, University of Glasgow (2024)
- PhD fellowship, Government of Flanders (Belgium)-IWT (2009)
- HSP Huygens scholarship, Nuffic (Netherlands) (2006)
Dr. Vande Voorde leads an active research team comprising postdoctoral scientists, a PhD student, and technical staff. His laboratory collaborates extensively with other research groups at the CRUK Scotland Institute, particularly those studying colorectal cancer, pancreatic cancer, and tumor microenvironment. He has secured significant funding through his recent fellowships to advance his research program.
The Vande Voorde Laboratory operates within the CRUK Scotland Institute at Garscube Estate in Glasgow. The lab maintains strong connections with Professor Owen Sansom's group and collaborates across multiple research themes including liver cancer, pancreatic cancer, and mitochondrial reprogramming in cancer. His team's work bridges basic cancer metabolism research with potential clinical applications for improving cancer therapy outcomes.
