Jerome I Rotter

Jerome I Rotter is a Professor-in-Residence at the David Geffen School of Medicine, University of California, Los Angeles, with joint appointments in the Departments of Pediatrics and Human Genetics. His research focuses on genetic mechanisms underlying cardiometabolic diseases, leveraging large-scale genomic studies.

Dr. Rotter's primary fields of interest include human genetics, cardiovascular disease epidemiology, diabetes research, and genomic medicine. He leads investigations into the genetic basis of conditions like atherosclerosis, diabetic retinopathy, and lipid disorders, often through multi-ethnic cohorts.

His recent publications (2023-2025) demonstrate a strong emphasis on genome-wide association studies (GWAS), multi-omics integration, and genetic risk prediction across diverse populations. Research themes include genetic determinants of metabolic dysfunction-associated steatotic liver disease (MASLD), von Willebrand disease, type 2 diabetes complications, and cardiovascular biomarkers.

As Principal Investigator, Dr. Rotter has secured substantial NIH funding including:

• Hispanic Latino Lipid Consortium (NIH R01HL142302, 2018-2022)
• Genetics of Diabetic Retinopathy in Hispanics (NIH R01EY014684, 2004-2013)
• Multi-Ethnic Study of Atherosclerosis (NIH R01HL071205, 2003-2010)
• Genetic Factors in Keratoconus (NIH R01EY009052, 1993-2020)

He actively collaborates in large consortia like the NHLBI Trans-Omics for Precision Medicine (TOPMed) program but does not lead a dedicated laboratory team.