معرفی
Jeremy Hirota is an Associate Professor at the McMaster School of Biomedical Engineering and holds an affiliation with the Department of Medicine at McMaster University. He leads a translational research program in lung exposure science, focusing on particulate matter, cigarette smoke, and cannabis smoke effects on respiratory health. His work integrates 3D bioprinting and microphysiological systems to model lung immunity and disease mechanisms.
Education: Ph.D. in Biomedical Engineering from McMaster University (2009).
Research Interests: Hirota’s lab develops advanced in vitro models incorporating dynamic microenvironments, including 3D-printed lung tissues and bioinks derived from decellularized human lung matrices. His work addresses lung fibrosis, immune responses to environmental exposures, and translational applications of biomaterials. Key projects include:
- Development of cannabis smoke exposure models to study developmental and respiratory impacts
- Creation of mechanically dynamic lung-on-a-chip systems for drug testing
- Commercialization of bioink formulations via patents and startups like Infinotype
Articles Trends: His 150+ publications span lung epithelial biology, biomarker discovery (e.g., CXCL10), and 3D bioprinting methods. Recent work highlights cannabis smoke’s immunosuppressive effects on viral infections and novel bioink applications.
Entrepreneurship: Co-founder and CEO of Infinotype (2020-present), a biotech company developing diagnostic tools like AlignDx sequencing software. Holds 5 IP disclosures, including bioinks and therapeutic inhibitors.
Labs/Teams: Leads the Lung Exposure & Engineering Lab at McMaster, collaborating with SickKids Hospital on lung disease models. Active in commercializing research through partnerships with regional innovation centers.
