Jennifer Murphy

Jennifer M. Murphy is an Associate Professor in the Department of Molecular and Medical Pharmacology at the University of California, Los Angeles (UCLA). Her primary affiliation is within the School of Medicine. Dr. Murphy specializes in the development of radiopharmaceuticals and molecular imaging agents, particularly focusing on positron emission tomography (PET) tracers for oncological and biomedical applications. Her research integrates organic synthesis, radiochemistry, and computational methods to design novel bioorthogonal reactions and fluorination strategies for imaging and therapeutic purposes.

Her work emphasizes the creation of efficient, chemoselective labeling methods for peptides and antibodies, enabling精准 targeting of biological systems. Notable projects include the development of brain-penetrant EGFR inhibitors for glioblastoma imaging and thiol-reactive fluorinated synthons for peptide functionalization. Dr. Murphy collaborates extensively with researchers in nuclear medicine, oncology, and computational chemistry, as evidenced by co-authorships with experts like Caius Radu and Michael van Dam.

Publications highlight advancements in silicon-fluoride acceptors, gold(III) reagents for aqueous-phase fluorination, and automated radiosynthesizer protocols. These contributions reflect her commitment to advancing PET imaging technologies and their clinical applications in diagnostics and personalized medicine.