Jennifer Frampton

Jennifer Frampton, DO, MPH, is an Assistant Professor of Medicine (Cardiovascular Medicine) and Associate Program Director of the Interventional Cardiology Program at Yale School of Medicine. She specializes in interventional cardiology, focusing on complex coronary interventions, chronic total occlusions (CTO), and geriatric cardiovascular care. Dr. Frampton’s clinical practice emphasizes patient-centered care for coronary artery disease and post-procedural management. Her research investigates dual antiplatelet therapy optimization, outcomes in older adults undergoing revascularization, and cardiovascular guidelines.

Education & Training:

• DO: Lake Erie College of Osteopathic Medicine (2014)
• MPH: University at Albany, School of Public Health (2010)
• Residency: Dartmouth-Hitchcock Medical Center (2017)
• Cardiology Fellowship: Dartmouth-Hitchcock Medical Center (2020)
• Interventional Cardiology Fellowship: Dartmouth-Hitchcock Medical Center (2021)

Research Interests: Dr. Frampton’s work bridges clinical practice and population health, with a focus on:
– Sex differences in cardiovascular treatment outcomes
– Guideline adherence and older adult representation in clinical trials
– Innovations in PCI techniques for calcified lesions

Publications & Awards:

• Lead/co-author on 30+ peer-reviewed articles (2022–2025)
• SCAI’s 30 in Their 30s Award (2025)
• Contributions to AHA/ACC/SCAI clinical guidelines

Grants & Mentorship: Active in mentoring trainees in interventional cardiology and cardiovascular research. Collaborates with teams analyzing national cardiovascular datasets for quality improvement initiatives.

Labs/Teams: Part of the Complex High-Risk Interventional Procedures (CHIP) Program and Chronic Total Occlusion (CTO) Program at Yale Medicine.