Jelmer Prins

Jelmer Prins serves as Program Leader at the Faculty of Medical Sciences, University of Groningen, specifically within the Senescence, Stem Cells, and Inflammation (SSI) and Translational Immunology Groningen (TRIGR) research groups. With 89 research outputs including 48 articles and 19 review articles, his work significantly contributes to reproductive immunology and pregnancy-related research.

Dr. Prins' research primarily focuses on maternal-fetal immune interactions, with particular expertise in placental immunology, macrophage biology, and regulatory T cells during pregnancy. His fingerprint analysis reveals strong concentrations in pre-eclampsia (100%), macrophage studies (81%), regulatory T cell research (77%), and fetal growth restriction (77%). His work examines how immune cells function in the decidua and placenta during both healthy and complicated pregnancies, with special attention to conditions like systemic rheumatic diseases and fetal growth restriction.

Analysis of his recent publications shows consistent focus on placental immune cell subsets, particularly macrophages, and their role in pregnancy complications. His research often employs both human clinical studies and mouse models to investigate maternal immune responses to fetal allogeneity, with significant work on interventions like sildenafil treatment for fetal growth restriction. The Dutch STRIDER study represents one of his major collaborative clinical investigations.

Among his notable recognitions:

• The TWIN Cerclage (TWINC) study award (2022) for research on cerclage effectiveness in twin pregnancies
• 2018 honors for characterizing microglia and placental macrophages in pregnancy
• 2018 award for establishing a network of reproductive immunology experts
• 2018 recognition for research on maternal obesity's effects on macrophages

Dr. Prins actively contributes to the academic community through editorial work on Reproductive Sciences journal since 2020 and membership in the Dutch Immunological Society (NVVI) and European Placenta Group. His public engagement includes media contributions about preeclampsia and pregnancy-kidney disease relationships, demonstrating commitment to translating research into clinical practice and public understanding. His research receives support through grants including ZonMw's Translationeel Onderzoek program.

As Program Leader of the SSI and TRIGR research groups, Dr. Prins oversees investigations into senescence, stem cells, and inflammatory processes in reproductive contexts, with particular emphasis on how these mechanisms influence pregnancy outcomes and maternal health.