معرفی
Jeffrey R. Millman is Professor of Medicine and Biomedical Engineering at Washington University. His lab develops stem cell-derived pancreatic β cells for diabetes treatment, creating functional SC-β cells that reverse hyperglycemia in mice. Research combines biomedical engineering with stem cell biology to improve cell differentiation protocols.
Key Achievements:
- Developed 6-step protocol for functional SC-β cell generation
- Produced scalable suspension cultures (500M cells/batch)
- Demonstrated diabetes reversal in mouse models
Research Focus: Microenvironmental optimization of β cell differentiation, disease modeling using diabetic patient-derived iPSCs, and clinical translation of cell therapies.
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