Jeffrey Neitz

Jeffrey Neitz is a Professor in Pharmaceutical Chemistry at the University of California, San Francisco (UCSF) School of Pharmacy. He is affiliated with the UCSF AViDD Center, NCI Chemical Biology Consortium, ATOM Consortium, and Small Molecule Discovery Center. Collaborations include significant contributions with researchers such as Michelle Arkin, Adam Renslo, and James Fraser.

Education:

• Ph.D. in Organic Chemistry from University of Michigan (2003)
• B.Sc. in Chemistry and Music from Georgetown University (1994)

Research Interests focus on Pharmaceutical Chemistry, Chemical Biology, and Molecular Biology, with emphasis on drug discovery for infectious diseases like Chagas disease and schistosomiasis, enzyme inhibition, protein-protein interaction stabilization, and computational/structural approaches to drug design. His work spans AAA+ ATPase p97, coronavirus MPro, and kinase targeting.

Publications (2010-2025) demonstrate expertise in drug discovery, structural biology, and biochemistry, with recent studies on SARS-CoV-2 macrodomain inhibitors, 14-3-3 protein stabilizers, and KDM5A ligands. Earlier work includes cruzain inhibitors for Chagas disease and PLK1 inhibitors for parasitic diseases.