Jedd Wolchok

Jedd Wolchok is a Professor of Medicine and the Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine. He is a clinician-scientist conducting translational research on immunotherapeutic strategies for cancer, with a focus on melanoma, lung, breast, and bladder cancers. His work bridges pre-clinical studies and clinical trials, emphasizing immune checkpoint blockade, tumor metabolism, and combination therapies.

• Education: BA (Princeton University), MD, MS, PhD (New York University).
• Affiliations: Ludwig Institute for Cancer Research, Parker Institute for Cancer Immunotherapy, ECOG-ACRIN NCI Cooperative Group (Chair, Melanoma Committee).

Research interests include mechanisms of tumor resistance to immunotherapy, tumor antigenicity, and engineering CAR T cells. His lab investigates how tumor metabolism, microbiota-derived metabolites, and immunosuppressive cells like myeloid-derived suppressor cells and regulatory T cells impact therapy efficacy.

Notable awards include the AACR Rosenthal Memorial Award, Giants of Cancer Care, and election to the National Academy of Medicine. He has mentored Damon Runyon Awardees and contributed to pivotal clinical trials leading to FDA approvals of ipilimumab and nivolumab combinations.