معرفی
Professor Jean K Lim leads research in Microbiology at Columbia University, specializing in immunological mechanisms of viral and fungal infections. Her work focuses on host-pathogen interactions, antiviral immunity, and inflammatory responses during infections like SARS-CoV-2, West Nile virus, and Candida. She holds a PhD from the University of Maryland and conducted postdoctoral training at NIAID, NIH. Her research bridges basic immunology with clinical implications, particularly in understanding immune dysregulation and developing novel therapeutic strategies.
Education:
- PhD in Microbiology, University of Maryland
- NIAID Postdoctoral Fellowship, National Institutes of Health
Research Interests: Investigating the cellular and molecular mechanisms underlying immune responses to pathogens such as coronaviruses, flaviviruses, and fungal pathogens. Key areas include:
- Viral entry and immune evasion strategies
- Role of neutrophils and macrophages in antifungal defense
- Chemokine receptor regulation in neurotropic virus infections
- SARS-CoV-2 pathogenesis and long-term sequelae
Recent Work Trends: Her articles emphasize SARS-CoV-2-induced immunopathology (e.g., cardiac inflammation, skeletal muscle atrophy), the role of chemokine receptors like CCR5 in viral encephalitis, and translational studies on antiviral therapies. She also explores zoonotic virus risks and host genetic factors influencing infection outcomes.
Grants & Collaboration: Likely involves NIH-funded projects given her NIAID background, though specific grants aren't detailed here. Collaborations include studies on vaccine development and antifungal immunity mechanisms.
