Jan Hoeijmakers

Jan Hoeijmakers is an Associate Professor in the Department of Molecular Genetics at Erasmus University Medical Center in Rotterdam, Netherlands. With over 370 research outputs to his name, he is a prominent researcher in DNA repair mechanisms and aging biology.

• Institution: Erasmus University Medical Center
• Department: Molecular Genetics
• Position: Associate Professor

Hoeijmakers' research focuses on DNA repair pathways including Base Excision Repair, Nucleotide Excision Repair, and their connections to aging and progeroid syndromes. His work examines how DNA damage affects transcription and contributes to conditions like Xeroderma pigmentosum and Cockayne Syndrome. Recent research explores dietary interventions including fasting and protein restriction in modulating aging processes in DNA repair-deficient models.

His publication trends show a strong focus on the intersection of DNA repair mechanisms, aging processes, and metabolic interventions. Recent work examines how dietary restriction affects vascular aging, immune function, and cellular phenotypes in progeroid models, suggesting potential therapeutic approaches for age-related conditions.

Hoeijmakers has delivered numerous presentations including 'Hoe tikt de biologische klok?' (How does the biological clock tick?) in 2007 and 'DNA-reparatie en genetische degeneratie' (DNA repair and genetic degeneration) in 1999, demonstrating his longstanding commitment to public engagement about aging research.

With 54 supervised students documented in his profile, Hoeijmakers has made significant contributions to training the next generation of researchers in molecular genetics and aging biology. His research has garnered attention across multiple platforms including news outlets, social media, and academic networks.