James Tidball

James Tidball is a Professor at the David Geffen School of Medicine, University of California, Los Angeles, affiliated with the Department of Integrative Biology & Physiology and Department of Pathology and Laboratory Medicine. His research focuses on the interplay between the immune system and skeletal muscle in diseases like muscular dystrophy and age-related sarcopenia.

• Key Research Areas:
  • Muscular dystrophy pathophysiology
  • Immunomodulation of muscle regeneration
  • Nitric oxide signaling in muscle repair
  • Aging-induced muscle wasting

His publications highlight groundbreaking work on Klotho gene therapy, macrophage polarization, and NF-κB signaling in muscle diseases. Recent studies examine immune cell-targeted interventions and aging-related epigenetic changes in myogenesis.

• Technical Approaches:
  • Transgenic mouse models
  • Phenotypic analysis of immune/muscle interactions
  • Pharmaceutical intervention testing