James Akira Wohlschlegel

James Akira Wohlschlegel is a Professor in the Department of Biological Chemistry at the University of California Los Angeles (UCLA), where he leads a research program focused on proteomics, protein complex analysis, and molecular mechanisms across diverse biological systems. His work bridges fundamental biochemistry with translational applications in infectious diseases, metabolic disorders, and epigenetic regulation.

Dr. Wohlschlegel's research interests encompass:

• Advanced proteomic techniques and mass spectrometry methodologies
• Iron-sulfur cluster biogenesis and redox regulation
• Chromatin remodeling complexes and epigenetic mechanisms
• Host-pathogen interactions, particularly with Toxoplasma gondii and malaria parasites
• Mitochondrial biology and membrane protein functions

His laboratory has pioneered innovative approaches in proximity labeling and protein interaction mapping that have significantly advanced spatial proteomics. Recent work demonstrates his ability to integrate computational and experimental approaches to tackle complex biological questions across multiple model systems.

Dr. Wohlschlegel's research program shows consistent productivity with high-impact publications spanning top journals including Nature, Science, and Cell. His collaborative network extends across disciplines, reflecting the interdisciplinary nature of modern biochemical research and the broad applicability of his proteomic expertise.