معرفی
Dr. Jake Harris is an Associate Professor in the Department of Plant Sciences at the University of Cambridge and Head of the Chromatin & Memory Research Group. He is also a Royal Society University Research Fellow. His research focuses on understanding how chromatin impacts gene expression in plants, with particular interest in epigenetic memory and stress priming.
- Department of Plant Sciences, School of Biological Sciences
- University of Cambridge
- Downing Street, Cambridge, CB2 3EA
Harris employs a range of molecular biology tools, CRISPR-based precision (epi)genomics, and cutting-edge genomic and bioinformatic approaches including ChIP-seq, RNA-seq and ATAC-seq to assess chromatin dynamics. His research aims to understand how chromatin states are perpetuated to form epigenetic memories at a cellular level, with the ultimate goal of using this knowledge to impart stress 'memories' into naive plants so they are primed for challenges such as pathogen attack.
His research spans epigenetics, plant molecular biology, chromatin dynamics, and stress priming. Harris combines molecular, genomic, and computational approaches to engineer plant biology with potential implications for health and agriculture. His work has significant applications in developing more resilient crops through epigenome engineering.
Harris's publications demonstrate a strong focus on chromatin remodeling, DNA methylation, histone modifications, and their roles in plant stress responses and development. His research shows a progression from fundamental mechanisms of epigenetic regulation to potential applications in crop improvement.
Scientific Awards:
- Royal Society University Research Fellow
Harris leads the Chromatin & Memory Research Group, which investigates fundamental questions concerning chromatin's effect on transcription. His lab employs a variety of cutting-edge approaches to address basic questions with potential implications in health and agriculture. The group is supported by various funding sources that enable their innovative research in epigenome engineering and plant stress responses.
