معرفی
Jae-Kyung Lee is an Associate Professor in the Department of Physiology and Pharmacology at the University of Georgia's College of Veterinary Medicine. Her research investigates neuroinflammatory mechanisms in neurodegenerative disorders, with emphasis on Parkinson's disease, microglia biology, and Regulator of G-protein Signaling (RGS) proteins. Dr. Lee leads an active research laboratory exploring therapeutic interventions for neurodegeneration.
Education:
- BS (1997) and MS (1999) from Kyungpook National University, South Korea
- PhD (2005) from University of North Texas Health Science Center
- Postdoctoral training (2008) at University of Texas Southwestern Medical Center
Research Focus: Dr. Lee's work examines how inflammation influences neurodegenerative processes, particularly through microglial activation and immune signaling pathways. Her lab investigates RGS10's role in modulating neuroinflammation, natural killer cell functions in Parkinson's pathology, and oxidative stress mechanisms in neurodegeneration. Current projects explore alpha-synuclein clearance mechanisms and immune cell profiling in synucleinopathy models.
Publication Trends: Her recent articles demonstrate a strong focus on neuroimmune interactions in Parkinson's disease, particularly the regulatory functions of RGS proteins and natural killer cells. Research spans molecular mechanisms of neuroinflammation, animal models of neurodegeneration, and identification of novel therapeutic targets. Over 50% of recent publications directly address Parkinson's pathology and immune modulation.
Teaching:
- VPHY8020 Neuroanatomy (Instructor)
- VPHY8250 Integrative System Physiology II (Instructor)
- VPHY8010 Mammalian Cell Physiology (Course coordinator)
Laboratory: Leads the Lee Lab focused on neuroimmunology and neurodegenerative disease mechanisms.
