معرفی
Dr. Jacopo Ferruzzi is an Assistant Professor of Bioengineering at the University of Texas at Dallas (UTD), affiliated with the Erik Jonsson School of Engineering and Computer Science. He leads the Tissue Mechanics & Remodeling (TMR) Laboratory, focusing on the interplay between tissue mechanics and disease progression in cardiovascular systems and cancer. Prior to UTD, he held postdoctoral roles at Yale University and Boston University, where he specialized in cardiovascular biomechanics and cancer mechanobiology.
Dr. Ferruzzi holds a BS and MS in Biomedical Engineering from the University of Pisa, Italy, and a PhD in Biomedical Engineering from Yale University. His postdoctoral training at Boston University expanded his expertise into 3D cell culture techniques and label-free imaging for studying cancer biomechanics.
His research interests include biomechanics, mechanobiology, and computational modeling, with a focus on understanding how altered mechanical properties of tissues contribute to diseases like cardiovascular conditions and cancer. Specific projects explore tumor-stroma interactions, collagen remodeling in breast cancer, and the role of arterial stiffness in aging and hypertension.
His work integrates experimental and computational methods, such as fluorescence lifetime imaging microscopy (FLIM) and multiphoton microscopy, to analyze tissue dynamics. Recent studies highlight innovations like PD-L1-targeted photoactivable liposomes for pancreatic cancer therapy and biomechanical phenotyping of arterial sections in vivo/ex vivo.
Dr. Ferruzzi’s lab offers multidisciplinary training opportunities for graduate students and postdoctoral researchers. Current openings exist in his lab to investigate the mechanical basis of tumor invasion and vascular disease mechanisms.
He has collaborated extensively across institutions, including Texas A&M University, and his research has been published in high-impact journals spanning biomedical engineering, oncology, and cardiovascular science.
