Inta Liepniece-Karele

Inta Liepniece-Karele serves as Associate Professor in the Department of Pathology at the University of Latvia, with active research contributions spanning gastrointestinal and gynecological pathology. Her work aligns with UN Sustainable Development Goal 3 (Good Health and Well-being) through clinical medicine applications.

Her primary research focuses on Gastrointestinal Pathology and Cervical Cancer Research, particularly investigating Helicobacter pylori infection mechanisms, atrophic gastritis biomarkers, cervical intraepithelial neoplasia progression, and diagnostic applications of pepsinogens and HLA alleles. Recent work emphasizes non-invasive diagnostic techniques including breath volatile organic compound analysis for gastric cancer surveillance and high-risk HPV mRNA expression in cervical precancerous lesions.

Analysis of her 2023-2024 publications reveals strong thematic continuity in molecular diagnostics for cancer precursors, with increasing emphasis on multi-factorial risk prediction models integrating microbiome data, genetic markers, and clinical parameters. Her work bridges laboratory pathology with clinical implementation through biomarker validation studies.

As a leading expert in the EU-funded NanoTENDO project (2020-2023), she contributed to nanoparticle transfer research through endothelial barriers, collaborating with international partners on immunomodulator development. Her academic service includes expert roles for the Latvian Council of Science (2021-2024 and 2023-2026) in clinical medicine evaluations.

Media coverage highlighted her 2022 research on diagnostic antibodies and pepsinogens for corpus-restricted atrophic gastritis, demonstrating translational impact of her work. She regularly presents findings at international conferences, including 2023 oral presentations on HPV mRNA expression and poster presentations on KI-67 classification for cervical intraepithelial neoplasia.