Ingo Schmidt-Wolf

Prof. Ingo Schmidt-Wolf is a Professor at the University of Bonn's Department of Integrated Oncology, affiliated with the Center for Integrated Oncology (CIO) Bonn. His research focuses on developing adoptive T cell immunotherapies, particularly cytokine-induced killer (CIK) cells, and understanding immune mechanisms in cancer. He leads a team exploring treatments for hematologic malignancies and solid tumors, emphasizing translational research between clinical and preclinical models.

• Affiliations: CIO ABCD Network (Aachen-Bonn-Cologne-Düsseldorf), Universitätsklinikum Bonn
• Key research areas: Immuno-oncology, CAR-T/CAR-CIK therapies, tumor immunology, and biomarker discovery

Research interests include enhancing CIK cell efficacy via combination therapies (e.g., with HDAC inhibitors, PD-1/PD-L1 blockade), and investigating molecular mechanisms like NKG2D signaling and epigenetic regulators. His work has led to clinical trials in multiple myeloma, glioblastoma, and hepatocellular carcinoma.

Publications highlight advancements in CIK cell therapy, biomarker identification (e.g., PNPLA7, CSRP1), and preclinical models for CNS malignancies. He collaborates internationally through initiatives like the International Registry on CIK Cells (IRCC).

Prof. Schmidt-Wolf’s contributions span clinical translation of cellular therapies, precision oncology, and addressing challenges in cancer drug resistance and metastasis.