Inge de Liefde

Inge de Liefde is a Researcher in the Department of Anesthesiology at Erasmus MC, specializing in neonatal and pediatric anesthesia. Her work is deeply embedded in large-scale, multicenter clinical studies such as the NECTARINE cohort, focusing on anesthesia safety, critical events, and outcomes in early life.

Research Interests: Her primary research areas include neonatal anesthesia, microcirculatory monitoring in congenital heart disease, pharmacokinetics of drugs in neonates, and observational studies on anesthesia practice. She investigates risk factors for respiratory complications, intubation difficulties, and hemodynamic stability during surgery in infants.

The recent publications show a strong trend toward large observational and collaborative European studies, particularly in the context of cardiac surgery and anesthesia safety. Her work integrates clinical data with pharmacological modeling and outcome assessment, contributing significantly to evidence-based pediatric anesthesiology.

Scientific Contributions:

• Co-investigator in the NECTARINE study on anesthesia practice in neonates
• Contributor to pharmacokinetic modeling of allopurinol in neonates with heart disease
• Research on microcirculatory changes pre- and post-cardiac surgery
• Analysis of ventilation strategies and adverse respiratory events

Advising and Grants: While no direct students or grants are listed in the provided text, her involvement in major multicenter trials such as NECTARINE and CRUCIAL suggests active participation in grant-funded research and collaboration with senior mentors and principal investigators. She likely contributes to training and mentoring within the research team at Erasmus MC.

Labs and Teams: She is part of the Anesthesiology research group at Erasmus MC and collaborates extensively with the European Society of Anaesthesiology Clinical Trial Network, particularly through the NECTARINE Group. Her work involves interdisciplinary teams including pediatric anesthesiologists, intensivists, pharmacologists, and cardiovascular researchers.