معرفی
Dr. Indra Gupta is a Senior Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) at the Glen site and a Professor in the Department of Pediatrics, Faculty of Medicine and Health Sciences at McGill University. She specializes in the Division of Nephrology at the McGill University Health Centre (MUHC) and leads research in the Child Health and Human Development Program within the Centre for Translational Biology.
Her research focuses on understanding the basis for congenital defects in the kidneys and urinary tracts, which account for 40% of all cases of kidney failure in children. Dr. Gupta's laboratory employs cell lines, animal models, and samples from affected children to investigate these defects and identify potential therapeutic interventions. Her work spans developmental biology, molecular genetics, and pediatric nephrology with particular emphasis on vesicoureteric reflux, congenital anomalies of the kidney and urinary tract (CAKUT), and the genetic basis of kidney disorders.
Analysis of Dr. Gupta's recent publications reveals a consistent focus on the molecular mechanisms underlying kidney development and disease. Her research spans developmental biology, molecular genetics, and clinical pediatric nephrology, with particular emphasis on tight junction proteins (especially claudins), extracellular matrix components, and genetic factors contributing to urinary tract defects. Her work bridges basic science and clinical applications, aiming to translate findings into improved diagnostic and therapeutic approaches for children with kidney disorders.
Through her leadership at the RI-MUHC and McGill University, Dr. Gupta has established herself as a prominent researcher in pediatric nephrology and developmental kidney disorders. Her work continues to advance our understanding of congenital kidney diseases and their implications for children's health outcomes.
