Ian A. Cook

Ian A. Cook is a Professor in the Department of Psychiatry and Biobehavioral Sciences at the David Geffen School of Medicine, University of California, Los Angeles (UCLA), and a Research Scientist at the Semel Institute for Neuroscience and Human Behavior. He holds the Joanne and George Miller and Family Endowed Chair in Depression Research.

• Princeton University – B.A. with High Honors
• Yale University School of Medicine – M.D.
• UCLA Neuropsychiatric Institute – Psychiatry Residency and NIMH-funded Research Fellowship

Dr. Cook’s research focuses on neuromodulation techniques for treating psychiatric disorders, particularly major depressive disorder (MDD). His work includes transcranial magnetic stimulation (TMS), trigeminal nerve stimulation (TNS), and implantable medical devices. He investigates biomarkers for treatment outcomes, neurophysiological correlates of depression, and the use of neurostimulation in diverse populations such as adolescents and elderly patients.

Recent publications highlight advancements in the SAINT® Neuromodulation System, TMS optimization, and device development for neurological and psychiatric conditions. His studies often integrate quantitative EEG, functional connectivity analysis, and clinical trial data to refine treatment protocols.

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Dr. Cook’s leadership roles include contributions to psychiatric practice guidelines and serving as an examiner for the American Board of Psychiatry and Neurology. He holds patents in biomedical devices and methods, reflecting his innovation in neuromodulation technology.

His lab at the Semel Institute explores the intersection of neuroscience and clinical psychiatry, with emphasis on translating neurophysiological insights into therapeutic interventions. Current projects address challenges in medication discontinuation, comorbid disorders, and biomarker validation.