Hui Li

Hui Li is an Assistant Professor of Research Medicine at the University of Southern California, with research interests in epithelial ion transport physiology and metabolic regulation in kidney function. His work focuses on AMPK signaling in autosomal dominant polycystic kidney disease and acute kidney injury, employing molecular and cellular approaches to study membrane transport processes.

Li's research explores the intersection of cellular metabolism and renal physiology, particularly how AMPK regulates ion channels and transporters in kidney epithelial cells. His published work demonstrates expertise in experimental models ranging from cell cultures to animal models, with emphasis on sodium transport, aquaporin function, and vacuolar ATPase regulation.

His publications consistently address molecular mechanisms underlying kidney diseases and potential therapeutic interventions. Recent articles show translational focus on repurposing existing drugs like metformin and resveratrol for renal protection. Methodological approaches include ex vivo kidney slice models, phosphorylation studies, and functional assays of membrane transporters.

Li collaborates with clinicians and basic scientists to bridge molecular discoveries with pathophysiological applications. His work has implications for developing novel treatments for polycystic kidney disease, hypertension, and renal carcinoma.