Htoo Wai

Dr. Htoo Wai is a Research Fellow at the University of Southampton, affiliated with the Human Genetics and Genomic Medicine department. His research focuses on RNA splicing mechanisms in rare genetic diseases, particularly leveraging RNA sequencing and antisense oligonucleotide therapies. He collaborates closely with Prof. Diana Baralle's group, contributing to projects such as retinal oligonucleotide development and genetic diagnostics in rare lung diseases.

Current research interests include developing novel diagnostic pipelines using transcriptome analysis and investigating actionable mutation groups through targeted oligonucleotide design. His work bridges basic molecular research with clinical applications, aiming to improve genetic diagnosis and therapeutic strategies for rare disorders.

Key projects include 'Retinal specific oligonucleotide development through chemical modification' and 'Uplifting genetic detection of rare lung diseases'. His publications (2022-2024) highlight contributions to splicing variant analysis, RNA-first diagnostics, and translational therapies.