Houman Ashrafian

Houman Ashrafian is a Visiting Professor of Experimental Therapeutics at the University of Oxford, affiliated with the Ashrafian Group (Experimental Therapeutics and Clinical Pharmacology) and the Watkins Group (Inherited Heart Muscle Disease). His research focuses on the intersection of cardiac metabolism and function, particularly in cardiomyopathy and heart failure.

Research Themes: He investigates how metabolic dysregulation contributes to myocardial energy deficiency in heart failure, leveraging insights from cancer metabolism to develop novel therapeutic strategies. His work includes bench-to-bedside translation of metabolic modulators like perhexiline and the cardioprotective properties of fumarate and insulin.

Publication Trends: His recent articles span

• cardiomyopathy pathophysiology (2024, 2022)
• genetic profiling in UAE populations (2022)
• metabolic imaging in aortic stenosis (2019)
• immune-cardiometabolic interactions (2025)
• neurogenetic disorders (2024, 2021)
• HLA-linked infectious disease susceptibility (2019)