Hong-Jian Wei

Hong-Jian Wei, Ph.D., is a Research Assistant Professor at the Fralin Biomedical Research Institute at Virginia Tech Carilion (VTC), where he conducts cutting-edge research in cancer biology with a focus on central nervous system malignancies such as diffuse midline glioma (DMG) and glioblastoma. He is a key member of the Wu Lab and collaborates extensively with interdisciplinary teams to develop innovative therapies.

• Position: Research Assistant Professor
• Institution: Fralin Biomedical Research Institute at VTC
• Email: hjwei@vtc.vt.edu

Dr. Wei holds a Ph.D. in Cancer Biology from Taipei Medical University, Taiwan, and completed postdoctoral training at Columbia University Medical Center. His research expertise lies in tumor biology, the cancer microenvironment, and novel therapeutic strategies including focused ultrasound (FUS)-mediated blood-brain barrier opening to enhance drug delivery and immune modulation in brain tumors.

His recent publications (2021–2025) demonstrate a strong focus on translational neuro-oncology, particularly in improving treatment outcomes for pediatric and adult brain cancers through combination therapies involving radiotherapy, FUS, and targeted agents. His work frequently appears in high-impact journals such as Neuro-Oncology, Cancer Discovery, and Science Translational Medicine, highlighting his contributions to understanding tumor heterogeneity, epigenetic regulation, and therapeutic resistance.

While no specific awards are listed in the provided text, his consistent publication record and collaborative research indicate significant scientific impact. Dr. Wei's work often involves mentorship of junior researchers and trainees, though formal advisees are not explicitly named. His research integrates molecular biology, imaging, and computational approaches to advance cancer treatment paradigms.