Holly Elizabeth Corkill

Dr. Holly Elizabeth Corkill serves as a Clinical Assistant Professor of Anesthesiology and Critical Care at the University of Pennsylvania, providing clinical care at Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center for adult patients. Her dual role bridges academic medicine and frontline anesthesia practice within the Penn Medicine system.

Her training pathway includes:

• Medical School: Geisinger Commonwealth School of Medicine
• Residency: Mount Sinai Hospital
• Fellowship: Mount Sinai Hospital

Research spans cardiac anesthesia, critical care, and translational physiology with three distinct foci: 1) Mechanisms of vasoplegia after cardiac surgery (2023), 2) Lipid management in chronic kidney disease (2018), and 3) Molecular regulation of bone formation via AFAP1/TGF-β pathways (2015-2017). This interdisciplinary trajectory demonstrates movement from basic science to clinically urgent perioperative complications.

Publication analysis reveals increasing clinical relevance over time, with recent work targeting vasoplegia—a life-threatening complication affecting 25% of cardiac surgery patients. Her 2023 study identifying plasma renin activity as a predictor represents direct translation of physiological research to surgical outcomes improvement.

No scientific awards are documented in available sources.

While specific grant details are unavailable, her continuous publication output suggests active research engagement. As a clinical faculty member, she participates in resident/fellow education though formal student advising isn't specified. Her work consistently involves multidisciplinary teams including cardiothoracic surgeons, nephrologists, and basic scientists.

Research is conducted through clinical departments rather than a dedicated laboratory, reflecting the practice-based nature of her anesthesia-focused investigations. Collaborations span Penn Medicine, Geisinger Health System, and Mount Sinai, maintaining connections with her training institutions.