Holger Sondermann

Holger Sondermann is a Professor at Christian-Albrechts-University of Kiel and leads the Structural Microbiology group at DESY’s Center for Structural Systems Biology (CSSB). He serves as Scientific Director of CSSB from 2024–2026. His research focuses on bacterial infection biology and fundamental cell biology, particularly mechanisms enabling bacteria to adapt to environmental stresses and form biofilms. He employs structural biology techniques, including modern X-ray sources like PETRA III, to study molecular processes relevant to pathogen control and chronic disease.

Academic career highlights include:

• 2024–2026: Scientific Director, CSSB
• 2020–present: Professor at Kiel University and Lead Scientist at DESY
• 2005–2020: Academic roles at Cornell University, including Assistant/Associate/Full Professor
• PhD (Biochemistry, 2001) and postdoctoral training at UC Berkeley and Rockefeller University

Research interests emphasize c-di-GMP signaling pathways, biofilm regulation, and enzymatic mechanisms in bacterial survival. His work bridges structural biology with clinical applications, targeting pathogens linked to chronic infections. Recent publications highlight breakthroughs in biofilm adhesin systems, diribonuclease activity, and malaria parasite invasion mechanisms.

Awards and grants are not explicitly listed in the provided text, but his leadership roles and prolific publication record reflect significant recognition in structural microbiology.

Labs/Teams: Head of the Structural Microbiology group at DESY’s CSSB, collaborating across disciplines to leverage advanced imaging techniques. Active in developing new radiation sources and methodologies for structural studies.