Henry Kwock Fong

Henry Kwock Fong is an Associate Professor of Ophthalmology at the University of Southern California (USC). His research focuses on understanding mechanisms underlying retinal degeneration, particularly age-related macular degeneration (AMD), and the role of non-visual opsins like RGR-opsin in retinal pathology. He investigates proteopathic processes linked to exon-skipping isoforms, oxidative stress pathways, and protein deposition in Bruch’s membrane.

Key research areas include retinal pigment epithelium (RPE) biology, G-protein-coupled receptor signaling, and neurodegenerative pathways such as the PINK1-parkin axis. His work combines molecular biology, cell culture models, and animal studies to explore AMD pathogenesis and potential therapeutic targets.

Publications from 2002 to 2024 highlight his contributions to understanding RGR-opsin dysfunction, drusen formation, and complement system activation in retinal diseases. Collaborations with institutions like CTSI (Clinical and Translational Science Institute) suggest involvement in translational research.