معرفی
Henry Charlier, Jr., Ph.D., is an Associate Professor in the Department of Chemistry and Biochemistry at Boise State University. His research focuses on enzymology and protein chemistry, with specific interests in carbonyl reductase, alcohol dehydrogenase, and phosphotriesterase. He teaches courses in biochemistry and chemical research at both undergraduate and graduate levels. Dr. Charlier has secured multiple grants, including NIH funding for studies on anthracycline metabolism and Idaho-INBRE projects.
Education:
- B.S. in Chemistry and Biology, University of Wisconsin-Stevens Point (1991)
- Ph.D. in Biochemistry, Medical College of Wisconsin (1996)
- Postdoctoral Fellowship in Biochemistry, University of Iowa (1997-2000)
Research Interests:
- Carbonyl reductase inhibition for anthracycline therapy optimization
- Electrostatic interactions in alcohol dehydrogenase coenzyme binding
- Enhancing phosphotriesterase activity for organophosphate detoxification
Funded Projects:
- NIH NCRR: Structure/function analysis of anthracycline reduction by human carbonyl reductase ($376K, 2004-2009)
- NSF-MSP Start Partnership: STEM Education for All (Co-PI, 2009-2011)
Teaching: Courses include College Chemistry, Biochemistry series, and special topics in enzyme kinetics. Emphasizes active learning and student responsibility in coursework.
Labs: Directs research in enzymatic mechanisms and protein engineering. Current projects involve modifying phosphotriesterase for pesticide/nerve agent decontamination.
