معرفی
Dr. Harold Mac Gillavry is an Associate Professor at the Cell Biology, Neurobiology and Biophysics department of Utrecht University's Faculty of Science. His research focuses on synaptic molecular organization and neuronal signaling mechanisms, particularly the nanoscale dynamics of synaptic proteins and their role in brain function and disorders like schizophrenia and autism.
- Studied Medical Biology (UvA) and earned PhD (2010) at VU Amsterdam
- Postdoctoral work with Dr. Tom Blanpied at University of Maryland Baltimore (2010-2014)
- Joined Utrecht University in 2014
Key research themes include:
- Subsynaptic nanodomain organization
- Receptor trafficking mechanisms
- Actin-cytoskeleton interactions
- Synapse ultrastructural analysis
- CRISPR/Cas9 applications in neurons
His 15 most recent publications (2018-2025) span synaptic neuroscience, antibiotic discovery (teixobactin), CRISPR methodologies, and schizophrenia genomics. Notable awards include NWO ALW-VENI, FEBS Return-to-Europe, NARSAD Young Investigator, and ERC Starting Grant.
Current work investigates how protein crowding, membrane lipid interactions, and structural scaffolding proteins like SHANK regulate synaptic plasticity through single-molecule imaging and quantitative proteomics.
