معرفی
Dr. Hao Lou is an Assistant Professor in the Department of Pharmaceutical Chemistry at the University of Kansas School of Pharmacy. His research integrates computational modeling and experimental approaches to advance drug formulation design, with emphasis on subcutaneous delivery systems for biologics and oral formulations.
Research focuses on:
- Computational pharmaceutics using machine learning and molecular dynamics
- Subcutaneous delivery of monoclonal antibodies and protein therapeutics
- In vitro emulation of subcutaneous absorption (ESCAR system)
- Formulation optimization for cyclic peptides and biologics
- Protein stabilization and drying techniques
Recent publications demonstrate novel applications of molecular dynamics simulations in predicting peptide properties, optimizing high-concentration protein formulations, and developing biorelevant dissolution methods. Work appears in pharmaceutical sciences journals covering formulation design and computational modeling.
Developed innovative platforms including an Emulator of Subcutaneous Absorption and Release (ESCAR) and protein-hyaluronic acid precipitation techniques. Contributes to advancing dry powder processing for inhaled formulations.
