Haike Antelmann

Prof. Dr. Haike Antelmann holds the W3-Professorship for Molecular Microbiology at the Institute of Biology-Microbiology, Freie Universität Berlin since 2015. She previously served as group leader at the Ernst-Moritz-Arndt-University of Greifswald (2006-2015) and completed her Habilitation there in 2009. Her research focuses on microbial redox biology, thiol-based stress responses in Gram-positive pathogens like Staphylococcus aureus and Streptococcus pneumoniae, and proteomic analysis of bacterial adaptation mechanisms. Key contributions include elucidating bacillithiol/mycothiol roles in protein protection and redox signaling.

Education: PhD (1998) and Habilitation (2009) from Ernst-Moritz-Arndt-University Greifswald, specializing in bacterial proteomics and stress physiology. Notable awards include the ERC Consolidator Grant (2013) and AcademiaNet membership (2015). She serves on editorial boards of BMC Microbiology, Molecular Microbiology, and Scientific Reports.

Research interests emphasize thiol-redox regulation in pathogenesis, including protein S-thiolation under oxidative/electrophilic stress and bacterial responses to host immune defenses. Her lab investigates bacillithiol's role in virulence and antibiotic tolerance, with recent work on allicin mechanisms and neutrophil phagosome interactions.

• Lab members: Postdocs (Eberhard Klauck, Vu Van Loi), PhD students (Huihui Li), and technical staff (Zeynep Gümüsboga)
• Key techniques: Proteomics, redox biosensors, transcriptomics, bacterial physiology studies
• Collaborations: GBM Study Group on Redox Biology, SPP1710 projects

Recent articles highlight Staphylococcus aureus adaptation to host-derived stressors (hypothiocyanous acid, itaconic acid) and mechanisms of antimicrobial resistance. Her work bridges basic microbiology with translational applications in infectious disease intervention.