Hagen Tilgner

Hagen Tilgner is an Associate Professor of Neuroscience at Weill Cornell Medical College. His research focuses on integrating long-read sequencing with single-cell and spatial transcriptomics to study RNA splicing, isoform expression, and their roles in neurodevelopmental disorders and cancers like gliomas.

• Education
  • M.Sc., Joseph Fourier University (Grenoble I) Faculty of Medicine (France), 2005
  • Ph.D., Pompeu Fabra University (Spain), 2011
  • M.Sc., University of Karlsruhe (Germany), 2005

Hagen's research has led to groundbreaking work on spatial isoform sequencing, uncovering cell-type-specific splicing patterns in cortical layers and diseases like Alzheimer's. His recent publications highlight advancements in precision medicine and isoform detection using RNA-Seq.

Key trends in his publications include:

• Long-read sequencing for isoform mapping
• Single-cell and spatial transcriptomics
• Splicing regulation in neurodevelopment and disease
• Algorithm development for RNA data analysis
• Targeting RNA variants in cancer
• Epigenetic and chromatin interactions