Guy Nagels

Dr. Guy Nagels is an Associate Professor of Cellular Neurophysiology at the Centre for Neurosciences (C4N) of the Vrije Universiteit Brussel (VUB) and associate chair of neurology at UZ Brussel. His clinical expertise lies in Multiple Sclerosis (MS) diagnosis, treatment, and rehabilitation, with a research focus on AI-supported modeling of cognition in MS and neurodegenerative disorders. He combines clinical neuroscience with computer science engineering to develop advanced cognitive models.

• University: Vrije Universiteit Brussel (VUB)
• School: Centre for Neurosciences (C4N)
• Role: Associate Professor & Associate Chair
• Collaborations: Oxford Centre for Human Brain Activity, Université Libre de Bruxelles, icometrix nv, BIODEM lab (University of Antwerp)

His research integrates Neuroscience, Artificial Intelligence, and Biomedical Engineering to address cognitive dysfunction in MS. He explores neurophysiological markers of cognition in dementia, brain aging biomarkers, and virtual reality rehabilitation tools. Recent projects focus on federated learning approaches and explainable AI for decoding cognitive decline from neuroimaging data.

Recent publications highlight AI-driven cognitive screening for MS, virtual reality interventions, and brain aging biomarkers in neurodegenerative diseases. His work emphasizes interdisciplinary methodologies, including neuroimaging and computational modeling.

Dr. Nagels supervises Master's students working on tDCS-induced electrical fields in MS, microbiome-age models, working memory assessments, neurophysiological processes in cognition, and deep learning applications for neuroimaging data.

The Cognition and Modelling Group at C4N collaborates with academic and industrial partners to advance understanding of neurological disorders through translational research and technology integration.