Gurudas Chakraborty

Dr. Gurudas Chakraborty serves as Project Leader and Scientific Advisor to the Director at RWTH Aachen University, with office space in Room A3.17 and contactable via +49 241 80-23149. He concurrently holds a governance position as Board of Trustees member for the Garg Foundation. His research bridges nanotechnology, biomaterials science, and biomedical applications through innovative molecular engineering approaches.

Chakraborty's primary research focuses on DNA nanotechnology and supramolecular chemistry, specializing in the design of functional DNA-based nanostructures for drug delivery and catalytic applications. His work addresses critical challenges in synthetic mRNA delivery systems, particularly regarding macrophage targeting and protein expression limitations, while developing novel biomaterials like hybrid pectin-fibroin microgels with tailored cross-linking properties. Recent investigations explore DNA's catalytic capabilities in non-aqueous environments and salt-free hybridization mechanisms through electrostatic PEGylation.

Analysis of his 2019-2025 publications reveals a cohesive research trajectory centered on DNA's structural versatility for nanoscale engineering. Key themes include overcoming biological barriers in therapeutic delivery (especially to liver macrophages), creating multifunctional biomaterials through supramolecular and covalent strategies, and expanding DNA's utility into non-physiological conditions like organic solvents. His work consistently integrates gold nanoparticles and hybrid polymer systems to develop advanced assemblies with biomedical applications, demonstrating interdisciplinary innovation across chemistry, materials science, and molecular biology.