Guan Xue Li

Dr. Guan Xue Li is an Assistant Professor at the Lee Kong Chian School of Medicine, Nanyang Technological University (NTU), and recipient of the 2016 Nanyang Assistant Professorship. She holds a PhD from the National University of Singapore (2009) and has held postdoctoral positions at the University of Geneva and the Swiss Tropical and Public Health Institute (Swiss TPH). Her research focuses on lipidomics and systems biology of lipid metabolism in infectious diseases, particularly tuberculosis, parasitic infections, and metabolic disorders. She leads the Systems Biology of Lipid Metabolism in Human Health and Diseases Laboratory and collaborates with global academic and industry partners.

Education: PhD in Biological Sciences, National University of Singapore (2009); Postdoctoral Training: Swiss TPH (2011–2016), SystemsX.ch Consortium (Switzerland).

Research Interests: Pioneering lipidomics tools to study host-pathogen lipid interactions, identifying drug targets and biomarkers for infectious diseases, and exploring lipid roles in diabetes-tuberculosis comorbidity. Her lab integrates lipidomics with genomics, proteomics, and epidemiology to address antimicrobial resistance and metabolic disease linkages.

Awards: 2016 Nanyang Assistant Professorship, MBC Paper of the Year 2009, and featured in MBoC's 20th Anniversary Favorites (2012). She secured the Ambizione Career Grant (Swiss NSF, 2011) and co-invented a patent on lipid-based diagnostic tools.

Advising & Grants: Supervises students like Lee Li Xian Megan and leads projects funded by international grants. Collaborates with local healthcare groups and institutions such as Swiss TPH.

Labs/Teams: Directs the Systems Biology of Lipid Metabolism Lab, focusing on translational research in lipid-driven disease mechanisms. The lab develops novel lipidomics tools and investigates microbial lipid pathways in pathogens like Mycobacterium tuberculosis.