Gregory Penoncello

Gregory Penoncello serves as an Assistant Professor in the Department of Radiation Oncology at the University of Colorado Anschutz Medical Campus School of Medicine. Board-certified in Therapeutic Medical Physics by the American Board of Radiology (2015), he maintains clinical practice at the University of Colorado Cancer Center and is affiliated with University of Colorado Hospital in Aurora, CO.

His academic credentials include:

• BS in Physics, University of Maine (2010)
• MS in Medical Physics, Vanderbilt University (2013)
• Additional Medical Physics Certification, Vanderbilt University (2015)

Dr. Penoncello's research centers on advancing radiation therapy safety and precision through medical physics innovations. His work spans dosimetric system validation, adaptive radiotherapy techniques, and novel device development for electron beam therapy and brachytherapy. Current projects focus on dose-volume histogram consistency across platforms, GammaTiles implementation for brain cancer, and skin dose optimization in head/neck treatments.

Analysis of his 2011-2024 publications reveals consistent emphasis on clinical translation of physics principles. Key trends include multicenter validation of commercial systems (2024), development of patient-specific shielding (2023), and GPU-accelerated proton therapy modeling (2022). His work bridges theoretical physics with direct clinical applications, prioritizing standardization and quality assurance in radiation oncology practice.

As a member of the American Association of Physicists in Medicine, Dr. Penoncello contributes to professional standards while maintaining active clinical responsibilities in radiation therapy planning and delivery at the University of Colorado Cancer Center.