Gregory De Crescenzo

Gregory De Crescenzo is a Full Professor at the Department of Chemical Engineering, Polytechnique Montréal, and a member of the Institute of Biomedical Engineering. His academic background includes a B.Sc. in Biochemical Engineering from INSA Toulouse and a Ph.D. in Biochemistry from McGill University.

• Education:
  • B.Sc. Biochemical Engineering, INSA Toulouse
  • Ph.D. Biochemistry, McGill University

Research Interests: De Crescenzo's work focuses on macromolecular interactions, kinetics and thermodynamics of biomolecule interactions, surface modification of biomaterials, SPR biosensors, microcalorimetry, analytical ultracentrifugation, tissue engineering, regenerative medicine, and gene therapy. His expertise spans biochemical engineering and biomedical materials, with a particular emphasis on analytical biochemistry techniques.

Article Trends: His recent publications (2025-2023) highlight advancements in surface plasmon resonance (SPR) biosensors for therapeutic protein analysis, hydrogel-based tissue engineering scaffolds, glycosylation characterization of monoclonal antibodies, and nanoparticle functionalization for drug delivery. Common subfields include protein glycosylation, biomolecular interactions, biosensor design, and bioactive material development.

Scientific Awards and Grants:

• NSERC Grant (2018): $1.65 million for a nanomedicines training program.
• TransMedTech Institute (2018, 2017): Project funding for biomedical innovations.
• Biomanufacturing Grant (2024): $20.5 million awarded to Polytechnique Montréal for local vaccine and biopharmaceutical production.

Advising and Collaborations: De Crescenzo has supervised over 35 graduate students, including 17 PhD and 18 Master’s theses. His students have explored topics such as surface plasmon resonance monitoring, chitosan-based implants, gold nanoparticle biofunctionalization, and growth factor immobilization strategies.

Labs and Teams: He leads research at Polytechnique Montréal’s RAMP-UP laboratories, part of a national initiative to enhance biopharmaceutical production. His work is supported by collaborations with institutions like Université Laval and funding from NSERC and TransMedTech Institute.