معرفی
Dr. Gerald Larrouy-Maumus is a Reader in Molecular Microbiology at Imperial College London's Department of Life Sciences, within the Faculty of Natural Sciences. His research focuses on understanding the environmental adaptation mechanisms of Mycobacterium tuberculosis (Mtb) during infection, particularly its survival strategies within host cells.
Education:
- Ph.D. in Molecular Microbiology, Toulouse (France)
- First postdoctoral research in Toulouse (France) on non-peptide-based vaccines using glycolipids
- Second postdoctoral research at MRC-NIMR London (UK) on functional annotation of orphan enzymes in Mtb
Research Interests: The laboratory uses advanced omics techniques (metabolomics, transcriptomics, proteomics, lipidomics) to study Mtb’s adaptation to hostile host environments such as nutrient-poor, acidic, and hypoxic niches. Key topics include cell-envelope biogenesis, metabolic pathways, and the role of asparagine and aspartate in Mtb virulence. The work aims to identify novel drug targets and elucidate resistance mechanisms in context of the host.
Affiliations:
- Agri Futures Lab
- Bacterial Pathogenesis
- CDT in Chemical Biology: Innovation in Life Sciences (supervisor)
- Centre for Bacterial Resistance Biology
- Institute for Molecular Science and Engineering
- Institute of Chemical Biology
Advising/Grants: Supervises students in the CDT in Chemical Biology program. No explicit grants listed in the provided text.
Labs/Teams: Leads a lab equipped with state-of-the-art mass spectrometry instruments (Agilent 6545 QToF, MALDI Biotyper Sirius system) and collaborates across multiple research centers at Imperial College London.
