معرفی
George Khelashvili is an Associate Professor of Systems and Computational Biomedicine at Weill Cornell Medical College, specializing in biophysics and computational biology. His research focuses on membrane protein dynamics, lipid-protein interactions, and structural mechanisms of GPCRs and transporters.
- Ph.D., Illinois Institute of Technology (2005)
- M.Sc. & B.Sc., Tbilisi State University (Georgia) (1999 & 1997)
His research investigates how cholesterol modulates membrane elasticity, lipid scrambling by GPCRs, and conformational transitions in transporters like MFSD2A. Recent work includes structural analysis of SARS-CoV-1 fusion peptide interactions and computational modeling of lipid dynamics.
Key trends in his publications (15 most recent) span membrane biophysics, GPCR signaling, transporter mechanisms, and disease-related studies (e.g., SARS-CoV, lymphoma pathogenesis). His work integrates molecular dynamics simulations with experimental validation.
Scientific Awards
- National Institute of Child Health & Human Development Grant (2023-2028) - Principal Investigator Subaward
Khelashvili collaborates on protein-membrane interactions and consults for Adiutrix Therapeutics, LLC. His contributions include methodological advancements in lipid mechanics, cholesterol regulation of membrane proteins, and kinetic modeling of amyloid formation.
