George Barbastathis

George Barbastathis is a Professor in the Department of Mechanical Engineering at the Massachusetts Institute of Technology (MIT) and leads the 3D Optical Systems Group. He is also affiliated with the Singapore-MIT Alliance for Research and Technology (SMART) Centre in Singapore.

• Academic Affiliation: Massachusetts Institute of Technology, School of Engineering, Department of Mechanical Engineering
• Research Focus: Machine learning and optimization for computational imaging, inverse problems, optical system design, and artificial optical materials.

His research integrates machine learning with physical modeling for applications in biomedical imaging, pharmaceutical manufacturing, and nanophotonics. Recent work explores uncertainty quantification, dynamical machine learning, and AI-driven diagnostics for glaucoma. His publications demonstrate expertise in deep learning, X-ray tomography, and optical metrology.

Advising highlights include mentoring Qihang Zhang, Iksung Kang, and Mo Deng. The group has contributed to AI-based particle size estimation, recurrent neural network approaches for transparent object imaging, and mechanistic modeling of lyophilization processes.

Key sponsors and collaborators include MIT's Computational Science and Engineering (CSE) program and the SMART Centre. The 3D Optical Systems Group focuses on optical design, biomedical imaging, and industrial inspection using advanced computational methods.