معرفی
Gaston van Hassel is a Professor in the Department of Cardiology at the University Medical Center Groningen's School of Medical Sciences. His research focuses on cardiovascular complications in congenital heart disease patients, particularly those with Fontan circulation.
His primary research interests include Cardiovascular Medicine, Iron Metabolism in heart failure, and Renal-Cardiac Interactions. Recent work examines how iron deficiency impacts exercise capacity and how renal function deterioration predicts mortality in Fontan patients. His studies integrate biomarker analysis (including N-terminal pro B-type natriuretic peptide) with clinical outcomes.
His publication trends reveal a specialized focus on Fontan circulation pathophysiology, with three key articles (2022-2024) establishing connections between iron status, renal function, exercise capacity, and survival. The research consistently employs multi-center collaboration and leverages biomarker data to understand physiological deterioration mechanisms.
Scientific contributions include:
- Establishing iron deficiency as a key modulator of exercise capacity in Fontan patients
- Demonstrating renal function deterioration as a mortality predictor
- Elucidating sex-specific mediation pathways involving iron biomarkers and BNP
Dr. van Hassel actively collaborates with international cardiovascular research teams, with recent work featured in JACC: Advances and Open Heart. His research contributes to UN Sustainable Development Goal 3 (Good Health and Well-being) through improved management of complex congenital heart disease.